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	<title>serotonin dysregulation &#8211; The Great Sleep blog</title>
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		<title>Serotonin Dysregulation in Narcolepsy Sleep Architecture: Why Your Brain&#8217;s Chemical Messenger Can&#8217;t Keep You Awake</title>
		<link>https://greatsleep.blog/serotonin-dysregulation-narcolepsy-sleep-architecture/</link>
		
		<dc:creator><![CDATA[Elaine Muncada]]></dc:creator>
		<pubDate>Wed, 24 Dec 2025 08:00:00 +0000</pubDate>
				<category><![CDATA[Narcolepsy]]></category>
		<category><![CDATA[amygdala and cataplexy]]></category>
		<category><![CDATA[autoimmune sleep disorder]]></category>
		<category><![CDATA[brain chemistry and sleep]]></category>
		<category><![CDATA[cataplexy]]></category>
		<category><![CDATA[dorsal raphe nucleus]]></category>
		<category><![CDATA[Emmanuel Mignot]]></category>
		<category><![CDATA[excessive daytime sleepiness]]></category>
		<category><![CDATA[hypocretin deficiency]]></category>
		<category><![CDATA[Jerome Siegel]]></category>
		<category><![CDATA[narcolepsy]]></category>
		<category><![CDATA[narcolepsy medications]]></category>
		<category><![CDATA[narcolepsy research]]></category>
		<category><![CDATA[narcolepsy symptoms]]></category>
		<category><![CDATA[narcolepsy treatment]]></category>
		<category><![CDATA[neurotransmitter dysfunction]]></category>
		<category><![CDATA[orexin neurons]]></category>
		<category><![CDATA[orexin receptor agonists]]></category>
		<category><![CDATA[REM sleep disorder]]></category>
		<category><![CDATA[serotonin and sleep]]></category>
		<category><![CDATA[serotonin dysregulation]]></category>
		<category><![CDATA[sleep architecture]]></category>
		<category><![CDATA[sleep disorders]]></category>
		<category><![CDATA[sleep neuroscience]]></category>
		<category><![CDATA[sleep-wake regulation]]></category>
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					<description><![CDATA[<p>In 2017, scientists made mice with narcolepsy stop collapsing by flooding one tiny brain region with serotonin—here's what that means for you.</p>
<p>The post <a rel="nofollow" href="https://greatsleep.blog/serotonin-dysregulation-narcolepsy-sleep-architecture/">Serotonin Dysregulation in Narcolepsy Sleep Architecture: Why Your Brain&#8217;s Chemical Messenger Can&#8217;t Keep You Awake</a> appeared first on <a rel="nofollow" href="https://greatsleep.blog">The Great Sleep blog</a>.</p>
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